Trial | NCT04216836  Report issue

Official Title

One Week of Magnesium Supplementation Lowers IL-6, Perceived Pain and Increases Post Exercise Blood Glucose in Response to Downhill Running

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    9
This study investigated the effect of magnesium supplementation on exercise performance and functional recovery in recreational endurance athletes in conjunction with measures of blood glucose, lactate, IL-6 and sIL-6R.
Magnesium status can directly affect circulating glucose concentrations both during and post exercise. In addition, magnesium supplementation has been shown to reduce circulating IL-6 concentrations post exercise in humans. It is conceivable that such observations are linked through the role of IL-6 in glucose regulation, possibly in combination with sIL-6R. Together, magnesium intake may have the potential to effect exercise performance and recovery through glucose availability. This in turn may be connected to the production of IL-6 and sIL-6R which have been established to influence exercise fatigue and perception of pain (muscle soreness).
Study Started
Jun 28
2018
Primary Completion
Mar 01
2019
Study Completion
Mar 01
2019
Last Update
Jan 03
2020

Dietary Supplement Magnesium oxide

Magnesium capsule

Dietary Supplement Placebo

Cornflour capsule manufactured to mimic the 166.6 mg magnesium capsule.

High magnesium diet (SUP condition) Experimental

Participants followed a low magnesium diet <260mg/day and consumed 500 mg/day of magnesium oxide. This was separated into 3 capsules, which were consumed at 6 hr intervals each day (8am, 2pm and 8pm). The supplementation period was 1 week.

Low magnesium diet (CON condition) Experimental

Participants followed a low magnesium diet <260mg/day and consumed 500 mg/day of placebo (cornflour). This was separated into 3 capsules, which were consumed at 6 hr intervals each day (8am, 2pm and 8pm). The supplementation period was 1 week.

Criteria 

Inclusion Criteria:

Regular recreational runner, running around 3 times per week
Capable of running 10 km in ~ 40 minutes.

Exclusion Criteria:

Any signs or symptoms of cardiovascular issues.
Any recent form of injury or illness.
Currently, or in the last 3 months, have consumed multivitamin supplements
Currently, or in the last 3 months, have consumed anti-inflammatory medications.
No Results Posted