Title
Effect of Intraoperative Dexamethasone on Post-op Dry Eye
Evaluation of Intraoperative Use of Dexycu on the Signs and Symptoms of Dry Eye
Phase
Phase 4Lead Sponsor
Hauser-Ross Eye InstituteStudy Type
InterventionalStatus
Completed Results PostedIndication/Condition
Dry Eye SyndromesIntervention/Treatment
dexamethasone intraocular suspension, 9% prednisolone ...Study Participants
40To compare the signs and symptoms of dry eye after cataract surgery between subjects randomized to receive intraoperative dexamethasone in addition to the use of a standard topical post-op treatment regimen.
Forty patients requiring cataract surgery will be randomized to treatment of post-operative inflammation with a single intraoperative dexamethasone injection plus a standard course of topical ophthalmic corticosteroid drops or the standard treatment alone. Dry eye testing will be administered at baseline, 1 week and 3 weeks following surgery.
single dose intracameral corticosteroid
topical ophthalmic steroid drop
dexamethasone intraocular suspension, 9% injected intracamerally at the time of cataract surgery + topical ophthalmic prednisolone acetate for 3 weeks post-operatively
topical ophthalmic prednisolone acetate for 3 weeks post-operatively
Inclusion Criteria: undergoing bilateral cataract surgery Exclusion Criteria: central corneal staining with fluorescein and/or a tear film osmolarity of greater than 340 in either eye
| Event Type | Organ System | Event Term |
|---|
Tear Film Osmolarity as measured on Tear Lab system; validated measure of Tear Film Osmolarity Osmolarity was reported in milliosmoles per liter (mOsmol/L)
