Trial | NCT04119297  Report issue

Title

Effects of Cold Application and Heparinoid on Periorbital Edema and Ecchymosis
Effects of Cold Application and Heparinoid on Periorbital Edema and Ecchymosis After Craniotomy

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    90
During surgery, blood leaking from damaged blood vessels spread to the periorbital area may cause periorbital edema and ecchymosis after anterior craniotomy. This study was carried out to determine the effects of the cold application and the local heparinoid on periorbital edema and ecchymosis after craniotomy.
Periorbital edema and ecchymosis are common after anterior craniotomy. Periorbital edema and ecchymosis are not complications, they are natural outcomes of surgical trauma. However, periorbital edema prevents pupil examination and causes the patient to experience fear and anxiety with accompanying ecchymosis. Periorbital edema rate after anterior craniotomy was 36.8-100%, ecchymosis rate was 62.5%, and 30% of patients with edema did not have a pupil examination for the first 36 hours after craniotomy.The present study was carried out to determine the effects of the heparinoid creams and regular cold application performed using gel packs in controlling periorbital edema and ecchymosis after craniotomy.
Study Started
Oct 01
2009
Primary Completion
Jul 01
2011
Study Completion
Jul 01
2011
Last Update
Oct 08
2019

Other Routine care

Routine care was applied to the periorbital area by clinical nurses. Periorbital edema, upper and lower eyelid ecchymosis of the patients were evaluated on the 3rd and 9th hours after craniotomy, and on the 1st, 2nd and 3rd days (twice daily) using the Kara & Gokalan's Scale

  • Other names: Irregular cold application or gauze bandages wetted with isotonic solution or once daily heparinoid cream application

Other Cold gel pack

Cold application was applied to the periorbital area for 20 minutes per hour beginning 3rd hour following craniotomy, except from 10pm-7 am, and for three days using gel pack cooled to -14ºC. Periorbital edema, upper and lower eyelid ecchymosis of the patients were evaluated on the 3rd and 9th hours after craniotomy, and on the 1st, 2nd and 3rd days (twice daily) using the Kara & Gokalan's Scale

  • Other names: Cold application

Drug Heparinoids Topical Cream

Heparinoid cream was applied to the periorbital area once at 3rd and 9th hours following craniotomy, and 4 times daily in the following 3 days. Periorbital edema, upper and lower eyelid ecchymosis of the patients were evaluated on the 3rd and 9th hours after craniotomy, and on the 1st, 2nd and 3rd days (twice daily) using the Kara & Gokalan's Scale

  • Other names: local heparinoid application

Control Active Comparator

Routine care (Irregular cold application or gauze bandages wetted with isotonic solution or once daily heparinoid cream application) of the clinic was applied.

Cold application Experimental

Cold application was applied for three days after craniotomy.

Heparinoid group Experimental

Heparinoid cream was applied for three days after craniotomy

Criteria 

Inclusion Criteria: The eligible participants were those

who were aged 18 years and older
who had Glasgow Coma Scale score > 15
who had no mental and physical problems that interfere with communication
whose vital signs were normal
who had no ptosis
who volunteered to participate and signed the informed consent form

Exclusion Criteria:The participants excluded from the study;

who had Glasgow Coma Scale score < 15
who died during surgery
ptosis formed after surgery
who refused to participate
No Results Posted