Trial | NCT03889431  Report issue

Official Title

Community Salt Testing and Relation of Iodine Intake to Visual Information Processing of Ethiopian Infants

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    106
This study evaluated efficacy of iodized salt for mothers and their six-month-old infants' thyroid hormones and visual information processing. Half of the participants received 450 g iodized salt for the household each week, while the other half received 225 ug iodine daily as a potassium iodide capsule.
Iodine is essential for the synthesis of thyroid hormones, and thyroid hormones regulate the metabolic processes of most cells and play important roles in human growth and development. Iodine deficiency disorders can have serious consequences on brain and physical development. In neonates iodine deficiency and hence insufficient supply of thyroid hormones could cause neonatal goiter, neonatal hypothyroidism, and endemic mental retardation.

Iodine deficiency disorders can be prevented and controlled by providing iodine and iodine can be provided in different ways. However, the United Nations Children's Fund and the World Health Organization jointly recommended salt iodization where iodized salt is accessible. Iodized salt is a safe, cost effective and sustainable strategy to ensure sufficient intake of iodine by all individuals and to improve maternal and infant health. However, although the effect of iodine on human health is well established efficacy of iodized salt has not been studied.
Study Started
Jan 02
2013
Primary Completion
Jan 30
2013
Study Completion
Aug 10
2013
Last Update
Mar 26
2019

Dietary Supplement Iodine capsule

225 µg of iodine daily as a capsule of potassium iodide

Other Iodized Salt

450 g iodized salt provided for the household weekly. Salt iodine content was 30 to 40 mg iodine /kg salt as KIO3

Capsule group Experimental

Group one received iodine capsule

Iodized salt group Experimental

Group two received iodized salt

Criteria 

Inclusion Criteria:

The women must be lactating and must have an infant less than or equal to one week old.
Mothers had to volunteer to participate in the study.

Exclusion Criteria:

Any hyperthyroidism symptoms manifested by nervousness, anxiety, heart palpitations, or rapid pulse.
If infants had fever, cough or severe (>3/day) diarrhea
Any allergic reaction such as acne, weakness, or foul breath
No Results Posted