Trial | NCT03843112  Report issue

Title

Modulating the Vaginal Microbiome After Implantation Failure
Modulating the Vaginal Microbiome After Implantation Failure A Randomized Placebo Controlled Study of Vaginal Lactobacilli Supplements

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    74
Vaginal microbiome has in studies shown a link with the outcome of fertility treatment. The investigators wish to determine if it is possible to change an unfavorable vaginal microbiome using lactobacilli loaded vaginal supplements.
Study Started
Mar 01
2019
Primary Completion
Jan 05
2021
Study Completion
Feb 27
2021
Last Update
Mar 23
2021

Drug Vivag Plus [lactobacillus rhamnosus, lactobacillus gasseri]

Contains two lactobacilli strains; l. gasseri and l. rhamnosus

Drug Placebo - Cap

Vaginal supplements

  • Other names: Placebo vaginal capsule

Vivag Plus Active Comparator

Vivag Plus vaginal supplements one capsule every night for ten days start cycle day 6-7.

Placebo Placebo Comparator

Placebo vaginal supplements one capsule every night for ten days start cycle day 6-7.

Criteria 

Inclusion Criteria:

unfavorable vaginal microbiome using ARTPreds test
non-smoker

Exclusion Criteria:

use of oral antibiotics oral probiotics between diagnosis and inclusion in the study
pregnancy at inclusion
allergy towards study drugs
No Results Posted