Trial | NCT03741686  Report issue

Title

Effect of Konjac-mannan in Individuals With Insulin-Resistance Syndrome
Beneficial Effects of Viscous Dietary Fiber From Konjac-Mannan in Subjects With the Insulin Resistance Syndrome

  • Phase

    Phase 2

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    11
To study whether a diet high in fiber from Konjac-mannan (KJM) has an effect on metabolic control in individuals with insulin resistance syndrome.
Study Started
Jan 31
1991
Primary Completion
Jun 30
1992
Study Completion
Jun 30
1999
Last Update
Nov 15
2018

Dietary Supplement konjac glucomannan

Konjac-mannan fiber-enriched biscuits (0.5 g/412KJ [100kcal] of glucommanan)

Dietary Supplement wheat bran

Wheat bran (hard red wheat bran) fiber enriched biscuits

Konjac-mannan Experimental

Konjac-mannan fiber-enriched biscuits with NCEP Step II metabolically controlled diet.

Placebo Placebo Comparator

wheat bran fiber biscuits with NCEP Step II metabolically controlled diet.

Criteria 

Inclusion Criteria:

Impaired glucose tolerant
Clinical absent of CHD
BMI less than 30 kg/m2
Presence of full insulin resistance syndrome
Reduced HDL cholesterol
Elevated serum triglycerides
Moderate hypertension

Exclusion Criteria:

Regular smoking
Regular alcohol consumption
Family history of premature coronary heart disease
Hypothyroidism
Renal, hepatic or gastrointestinal disease
Taking medications for hyperglycemia
Taking medications for hyperlipidemia
Taking medications for hypertension
No Results Posted