Trial | NCT03711006  Report issue

Title

The Effect of Fecal Microbiota Transplantation in Ulcerative Colitis
The Effect of Fecal Microbiota Transplantation in Ulcerative Colitis - A Case Study

  • Phase

    Phase 1/Phase 2

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    7
7 patients with active Ulcerative Colitis are treated with 25 multi-donor FMT Capsules daily for 50 days.
7 patients with active Ulcerative Colitis are treated with 25 multi-donor FMT Capsules daily for 50 days All patients are followed with regular follow up after 2,4,8,12,16, 20 and 24 weeks.
Study Started
Feb 01
2017
Primary Completion
Nov 30
2017
Study Completion
Nov 30
2017
Last Update
Oct 18
2018

Other Fecal Microbiota Transplantation Capsules

25 daily multi-donor FMT Capsules for 50 days

  • Other names: FMT Capsules

FMT treated patients Experimental

Seven patients with active Ulcerative Colitis treated with 25 multi-donor FMT Capsules daily.

Criteria 

Inclusion Criteria:

Diagnosed with Ulcerative Colitis (UC)
SCCAI between 4 and 10 at inclusion
On a stable dose of 5-aminosalicylic acid (5-ASA) or without current treatment.
Previous treatment with glucocorticoids, thiopurines and/or biological treatment was accepted.
Fecal Calprotectin > 250 mg/kg
Colonoscopy performed within the last 3 years
Capable of writing and speaking Danish
Attending regular follow-ups by a specialist in gastroenterology.

Exclusion Criteria:

Biological treatment within the last four weeks
Treatment with antibiotics within 48 hours before intervention
Alcohol use above current Danish guidelines (14 units/week for men and 7 units/week for women)
Pregnancy or planned pregnancy
Active cancer disease
Medical treatment of mental disorder
Other chronic gastroenterological disorder besides UC, Irritable Bowel Syndrome (IBS) or Reflux-disease.
No Results Posted