Title
Supplementing Intracytoplasmic Sperm Injection Handling Medium With Cytochalasin B
Cytochalasin B Supplementation to ICSI Handling Medium
Phase
N/ALead Sponsor
Ibn Sina HospitalStudy Type
InterventionalStatus
Completed No Results PostedIndication/Condition
InfertilityIntervention/Treatment
Cytochalasin B use in ICSI handling mediumStudy Participants
987Vienna Consensus has identified 10% damage rate after ICSI as a competency value. Despite the highest quality embryologists doing ICSI, degeneration sometimes occurs due to oocyte factors such as the fragile membrane, etc. Cytochalasin B serves to facilitate spindle or pronuclear transfer procedures helping to reduce the damage rate with no harm reported. Using Cytochalasin B during ICSI could serve to rescue some oocytes from the degeneration allowing for more chances of viable zygotes,
A medium with in-house supplementation of Cytochalasin B to decrease oocyte degeneration after ICSI and improve survival rate
Inclusion Criteria: All ICSI candidates patients Exclusion Criteria: No exclusion