Trial | NCT03626519  Report issue

Title

Effects of Menthol on Dyspnoea in COPD Patients
Effects of Menthol on Dyspnoea Induced by Exercise in COPD Patients

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    63
Chronic obstructive pulmonary disease (COPD) is characterised by non-reversible bronchial obstruction associated with systemic disorders and comorbid factors. Dyspnoea is a common symptom among patients with Chronic Obstructive pulmonary Disease (COPD). Dyspnea is the primary symptom limiting exercise and daily activities in these patients. It has been reported that breathing cold air could decrease dyspnoea induced by exercise and could improve exercise performance. The aim of this study is to carry out the effect of cooling sensation induced by menthol chewing-gum on dyspnoea and exercise performance among patients with COPD.
Study Started
Sep 23
2019
Primary Completion
Mar 12
2021
Study Completion
Mar 12
2021
Last Update
Apr 23
2021

Other Test with Menthol

patients will perform a Six-minute walk test according to American Thoracic Society guidelines

Other Test with placebo

patients will perform a Six-minute walk test according to American Thoracic Society guidelines

Test with placebo Placebo Comparator

Patients will chew a strawberry flavored chewing gum 5 minutes before perform one Six-minute Walk Test

Test with Menthol Experimental

Patients will chew a menthol flavored chewing gum 5 minutes before perform one Six-minute Walk Test

Criteria 

Inclusion Criteria:

a diagnosis of COPD
Dyspnea in daily living (2-4 on the modified medical research council dyspnea scale)
Clinically stable

Exclusion Criteria:

exercise contraindication Any musculoskeletal problems, cardiovascular or neurological comorbidities that limits exercise.
exacerbation during the study
Inability to chew or patients with swallowing disorders
No Results Posted