Clinical Drug Experience Knowledgebase

Criteria

Inclusion Criteria:

Patients who are confirmed no small cell lung cancer in accordance with the clinical diagnostic criteria , or by pathological histology or cytology examination which investigators think are suitable to accept The platinum-based doublet chemotherapy（According to RECIST V1.1,patients with no small cell cancers should have one measurable lesions at least ）.
ECOG performance status ≤2.
Laboratory inspection basically meets the following requirements： 1)Blood test：a. WBC≥ 4.0×109/L, b. ANC≥2.0×109/L, c. PLT≥100×109/L. 2)Biochemical test：a. ALT≤2.5 times the ULN;b. AST≤2.5 times the ULN ;c. Cr<=1.5 times the ULN.
Expected survival period is more than 3 months
Subjects join the study voluntarily, sign a consent form, have good compliance, and comply with follow-up.

Exclusion Criteria:

Patients need radiotherapy, targeted therapy, and other anti-cancer therapies during the trial.
Patients accepted radiation in the past 4 weeks before enrollment.
Previous bone marrow or stem cell transplant, or organ allograft.
Recently severe acute infection is not controlled; purulent or chronic infection is present and the wound is not healed.
Patients were or being suspected to be allergic to test drugs or related components.
Patients with hypersplenism, hyperthyroidism, adrenal cortical hypofunction, connective tissue disease, infectious diseases, such as viral hepatitis, tuberculosis infection and other diseases which can lead to the decrease of the white blood cells at the same time.
Patients with the symptoms of digestive system, such as nausea, vomiting, diarrhea, etc., that are not controlled will influence the test drug.
The central nervous system is metastatic and has symptoms.
History of another malignancy, except for in situ carcinoma of the cervix, adequately treated basal cell skin carcinoma.
Patients with severe heart, liver and kidney diseases; serious diseases of hematopoietic system; bleeding tendency.
Patients have a history of drug abuse and cannot be reined ;Patients with symptomatic, uncontrolled nervous disorders, mental illness or psychiatric disorder have less compliance.
Female patient is pregnant or breast-feeding, and those patients at childbearing age who are not willing to use methods of contraception.
Patients who are currently included in other clinical trials or accepted any experimental drugs in the past 4 weeks.
Any condition, in the investigator's opinion, is not in the best interest of the subject.