Trial | NCT03348241  Report issue

Title

Using Gum Arabic for Cancer Patients to Protect From Oral Mucositis Caused by Chemotherapy: ِِِAn Experimental Study
Randomized Controlled Trial on the Effect of Gum Arabic to Reduce Incidence of Oral Mucositis Induced by Chemotherapy for Cancer Patients

  • Phase

    Phase 2

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    Gum Arabic ...

  • Study Participants

    386
This study was designed to investigate the effect of Gum Arabic (GA) on cancer patients to prevent chemotherapy-induced oral mucositis. Cancer patients who will receive chemotherapy were divided into two groups; study "Gum Arabic" group (which received GA with chemotherapy) and control group (chemotherapy alone); and the participants were recruited to reach 190 patients in the study group and 184 patients in control group. This clinical trial was conducted in outpatient chemotherapy sections at Radiation and Isotopes Center of Khartoum. This study was designed to test the theory that say the chemotherapy-induced oral mucositis will significantly decrease after ingestion 30 grams as daily dose of Gum Arabic in a form of solution for six weeks during therapy.
Study Started
Oct 26
2015
Primary Completion
Aug 31
2016
Study Completion
Aug 31
2016
Last Update
Nov 20
2017

Drug Gum Arabic

Gum acacia, also known as Gum Arabic is exuded from acacia trees; mainly from Acacia Senegal (gum Hashab or Kordofan gum) which was used in this study.

  • Other names: Acacia Senegal

Drug Chemotherapy

Patients of control group and study group (Gum Arabic group) received chemotherapy according to type and stage of cancer.

  • Other names: Chemotherapy agents

Behavioral Lifestyle counseling

Lifestyle counseling pertaining to the optimal nutrition and daily routine for oral hygiene.

Gum Arabic group Experimental

Patients of study group was received a dose of 30 grams Gum Arabic per day as oral solution (dissolved in 250 ml purified water) for six weeks along with the chemotherapy prescribed addition to verbal instructions pertaining to the optimal nutrition and daily routine for oral hygiene.

Control group Other

Patients of control group was received only chemotherapy regimen and verbal counseling pertaining to the optimal nutrition and daily routine for oral hygiene.

Criteria 

Inclusion Criteria:

Patients whom well diagnosed with cancer in any stage were eligible for enrolment if chemotherapy is part of their treatment plan.

Exclusion Criteria: Patients were excluded if

they had received recent previous chemotherapy or radiotherapy,
they had oral mucositis or periodontitis,
there is evidence of any systemic diseases.
No Results Posted