Trial | NCT03218579  Report issue

Official Title

Endoscopic Assessment and Prediction of Microbiome-modifying Interventions

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Unknown status

  • Study Participants

    45
The investigators would like to examine the extent of gut microbiome rehabilitation in healthy people after the consumption of antibiotics.

Outcomes of probiotic treatment versus bacteriotherapy will be compared.
The investigators would like to examine the extent of rehabilitation of the composition and functioning of the intestinal bacteria in healthy people after the consumption of antibiotics.

Since the digestive mocus enables the connection between the host and the bacteria that live within it, the investigators would like to characterize the microbiome in the different areas along the digestive system - before antibiotic treatment and after rehabilitation by probiotic treatment versus bacteriotherapy.
Study Started
Feb 01
2013
Primary Completion
Dec 30
2019
Anticipated
Study Completion
Dec 30
2020
Anticipated
Last Update
Jul 21
2017

Dietary Supplement Probiotic treatment

4 weeks of probiotic treatment after 7 days of antibiotics (Metronidazole+Ciprofloxacin)

Biological Bacteriotherapy

Bacteriotherapy (autologous fecal microbiota transplantation) after 7 days of antibiotics (Metronidazole+Ciprofloxacin)

No intervention No Intervention

No intervention after antibiotic treatment.

Probiotic microbiome rehabilitation Active Comparator

Probiotic treatment after antibiotic treatment.

Bacteriotherapy microbiome rehabilitation Active Comparator

Bacteriotherapy after antibiotic treatment.

Criteria 

Inclusion Criteria:

Healthy volunteers
Age: 18 years and up
Gender: women and men

Exclusion Criteria:

Pregnancy
Age under 18 years
antibiotic treatment 3 months prior to enrollment
Viral Hepatitis
HIV positive
No Results Posted