Trial | NCT02889341  Report issue

Official Title

Valuation of Variable Dose of Docosahexanoic Acid for the Improvement of the Parameters of Male Fertility

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    60
Sperm parameters will be examined before DHA (DHA=Docosahexanoic Acid) consumption, after one months and after 2 months taken Docosahexanoic Acid or placebo.
Prospective, randomized, double blind, placebo-controlled intervention study within individuals. Assisted reproduction unit and academic research laboratory. One hundred an eighty human semen samples from 60 infertile patients of IVI Sevilla clinic were finally included. Assessment of oxidative stress, apoptosis, lipid peroxidation, mitochondrial membrane potential, DNA fragmentation and standard sperm parameters before and after supplementation with different DHA doses (0.5, 1 and 2 g) or placebo for 1 and 3 months.
Study Started
Oct 22
2013
Primary Completion
May 26
2015
Study Completion
Mar 31
2017
Last Update
Aug 02
2017

Dietary Supplement DHA

  • Other names: Docosahexaenoic acid

Other Placebo

Placebo Placebo Comparator

Placebo

500 mg DHA/day Active Comparator

500 mg DHA/day

  • Dietary Supplement DHA

1g DHA/day Active Comparator

1g DHA/day

  • Dietary Supplement DHA

2g DHA/day Active Comparator

2g DHA/day

  • Dietary Supplement DHA

Criteria 

Inclusion criteria:

1 year of infertility
> 10 mill/ml of sperms
Motility < 60% progressive
Morphology < 2% (WHO 2010)

Exclusion criteria:

No meeting the inclusion criteria.
No Results Posted