Trial | NCT02845622  Report issue

Title

Effects of Hazelnuts and Cocoa on Metabolic Parameters and Vascular Reactivity
Effects of Hazelnuts and Cocoa on Metabolic Parameters and Vascular Reactivity in Healthy Subjects: A Randomized Controlled Study

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    61
This study aims to assess the effects of hazelnuts, cocoa, and the combination of both on vascular reactivity and metabolic profile. Participants, divided in six groups, will receive one of these breakfast integrations for 14 days:

group 1) 30 g peeled hazelnuts;

group 2) 30 g unpeeled hazelnuts;

group 3) snack with 30 g peeled hazelnuts;

group 4) snack with 2.5 g cocoa powder;

group 5) snack with 30 g peeled hazelnuts and 2.5 g cocoa;

group 6) empty snack, control group.
In the last few years, the prevalence of overweight and obesity has increased in all age groups. The European Food Safety Authority stated "cocoa flavanols help maintain endothelium-dependent vasodilation, which contributes to normal blood flow". Several studies reported that a daily consumption of hazelnuts reduces the risk of cardiovascular disease. The hypothesis of this study is to demonstrate a beneficial effect of hazelnut and cocoa diet integrations on vascular reactivity and endocrine-metabolic parameters.
Study Started
Jun 30
2014
Primary Completion
Mar 31
2015
Study Completion
Mar 31
2015
Last Update
Sep 09
2016
Estimate

Dietary Supplement Hazelnut

This dietary supplement contains 30 g of hazelnut.

Dietary Supplement Cocoa

This dietary supplement contains 2.5 g of cocoa powder.

Dietary Supplement No hazelnuts / No cocoa

This dietary supplement does not contain hazelnut nor cocoa powder.

Dietary Supplement Cream

This dietary supplement is just a cream obtained by grinding hazelnuts.

Dietary Supplement Snack

This dietary supplement is a commercial snack containing either hazelnut or cocoa or both.

30g peeled hazelnuts cream Experimental

Every person in this group will receive a 30 g peeled hazelnuts cream as an integration to his usual breakfast, and will be asked not to change his diet and physical activity during the 2-week trial.

30g unpeeled hazelnuts cream Experimental

Every person in this group will receive a 30 g unpeeled hazelnuts cream as an integration to his usual breakfast, and will be asked not to change his diet and physical activity during the 2-week trial.

snack w/ 30g peeled hazelnuts Experimental

Every person in this group will receive a snack with 30 g peeled hazelnuts as an integration to his usual breakfast, and will be asked not to change his diet and physical activity during the 2-week trial.

snack w/ 2.5g cocoa powder Experimental

Every person in this group will receive a snack with 2.5 g cocoa powder as an integration to his usual breakfast, and will be asked not to change his diet and physical activity during the 2-week trial.

  • Dietary Supplement Cocoa
  • Dietary Supplement Snack

snack w/ 30g peeled hazelnuts+2.5g cocoa Experimental

Every person in this group will receive a snack with 30 g peeled hazelnuts and 2.5 g cocoa powder as an integration to his usual breakfast, and will be asked not to change his diet and physical activity during the 2-week trial.

empty snack Placebo Comparator

Every person in this group will receive an empty snack as an integration to his usual breakfast, and will be asked not to change his diet and physical activity during the 2-week trial.

Criteria 

Inclusion Criteria:

BMI 18.5-24.9 kg/m2

Exclusion Criteria:

diabetes mellitus
glucose intolerance
dyslipidemia
metabolic syndrome
allergies
No Results Posted