Title
Sildenafil Citrate in Frozen Embryo Transfer
Sildenafil Citrate for Endometrial Preparation in Frozen-thawed Embryo Transfer Cycles
Phase
Phase 2Lead Sponsor
Omar Ahmed El Sayed SaadStudy Type
InterventionalStatus
Completed No Results PostedIndication/Condition
InfertilityIntervention/Treatment
estradiol sildenafil ...Study Participants
90Comparison between usage of Sildenafil citrate with estradiol valerate or estradiol valerate alone in endometrial preparation and outcome of frozen-thawed embryo transfer cycles.
estradiol valerate 2mg every 12 hours orally starting from the second day of the menstrual cycle till reaching trilaminar endometrial pattern and endometrial thickness 8 mm or more
Sildenafil citrate 25 mg every 6 hours orally in combination with estradiol valerate 2mg every 12 hours orally starting from the second day of the menstrual cycle till reaching trilaminar endometrial pattern and endometrial thickness 8 mm or more
Inclusion Criteria: all cases have at least 2 good quality blastocysts available for transfer Exclusion Criteria: uterine structural abnormalities advanced uterine disease hydrosalpinx and pyosalpinx