Title
Morphine Versus Ketorolac in Renal Colic
The Analgesic Effects of Morphine Versus Ketorolac in Renal Colic
Phase
Phase 4Lead Sponsor
Bucharest Emergency HospitalStudy Type
InterventionalStatus
Unknown statusIndication/Condition
Renal ColicStudy Participants
100The study is prospective, double blinded, randomised controlled and has the purpose to compare the analgesic effects of ketorolac or morphine intravenous in renal colic.
The study will take place in the Emergency Department of the Clinical Emergency Hospital Bucharest and will compare the analgesic effects of ketorolac tromethamine against morphine in renal colic.
The patients will be randomised to receive either ketorolac 30 mg intravenous (diluted in 20 ml of 0,9% saline) or morphine 0,1 mg/kg weight intravenous. A scale of 1-10 will be used for measuring the pain, and the effects of the treatment will be evaluated at 15 minutes and 30 minutes from the administration of the drugs. After 30 minutes if there is no significant reduction of the pain a rescue therapy will be used : chlorhydrate drotaverine 40 mg, xilocaine 100 mg, both diluted in 100 ml saline and the other medication not used from the study (morphine or ketorolac tromethamine).
The patients randomised to this arm they will receive 30 mg intravenous ketorolac.
The patients randomised to this arm they will receive 0,1 mg/kg intravenous morphine.
Inclusion Criteria: clinical diagnosis of renal colic grade 5 pain on a 1-10 visual pain scale Exclusion Criteria: contraindications of ketorolac or opioids pregnancy allergies to ketorolac or opioids refusal of participation
