Trial | NCT02766855  Report issue

Title

Efficacy of Topical Cysteamine in Nephropathic Cyctinosis

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    cysteamine ...

  • Study Participants

    26
The aim of this study is to evaluate the efficacy of topical cysteamine eye drops in the treatment of corneal cystine crystals deposits in patients with nephropathic cystinosis.
A total of 26 patients with nephropathic cystinosis were included in this prospective study. Patients were evaluated for improvement of corneal cysteine deposits crystals and photophobia following treatment with topical 0.55% cysteamine eye drops.
Study Started
Jan 31
2004
Primary Completion
Dec 31
2012
Study Completion
Mar 31
2016
Last Update
May 10
2016
Estimate

Drug Cysteamine

Patients were asked to use topical cysteamine 0.55% eye drops every 2 hours while awake to both eyes.

cysteamine eye drops Experimental

Patients used cysteamine eye drops every 2 hours while awake to both eyes.

Criteria 

Inclusion Criteria:

patients with confirmed diagnosis of nephropathic cystinosis
leucocyte cystine concentration level of more than 2.0 nmol half-cystine/ mg protein
clinical evidence of tissue deposition of cystine and tissue damage due to cystinosis

Exclusion Criteria:

Allergy to cysteamine
No Results Posted