Trial | NCT02752594  Report issue

Title

Consumption of Probiotics on Salivary Bacteria Causing Dental Caries
Evaluation of the Consumption of Probiotics on the Bacteria Causing Dental Caries: A Randomised Clinical Trial

  • Phase

    Phase 2/Phase 3

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    40
Dental caries is a multifactorial disease effecting majority of the human population.One of the etiological factor causing dental caries is salivary mutans streptococci. Reducing the levels of this bacteria in the saliva can significantly reduce the incidence of dental caries. A non-invasive intervention, such as the administration of probiotics reduced the salivary mutans streptococci levels.
40 candidates were selected from a pre-determined group and were randomly assigned to two groups. Group A (n=20) was administered probiotic drink and Group B (n=20) was administered placebo for 14 consecutive days. Saliva was collected on day 1 and day 15 to compare the salivary mutans streptococci levels.
Study Started
Apr 30
2015
Primary Completion
Apr 30
2015
Study Completion
Apr 30
2015
Last Update
Apr 27
2016
Estimate

Biological probiotic

Probiotic was administered for a period of 14 consecutive days. Saliva was collected on Day 1, before intervention and on Day 15, after intervention

  • Other names: bacillus coagulans

Other placebo

placebo was administered for a period of 14 consecutive days. Saliva was collected on Day 1, before intervention and on Day 15, after intervention

probiotic Experimental

2 mg of probiotic powder mixed in 10 ml of distilled water

placebo Placebo Comparator

10 ml of distilled water

Criteria 

Inclusion Criteria:

Decayed Missing Filled Surfaces less than or equal to 6
Brushes twice daily

Exclusion Criteria:

undergoing orthodontic treatment
topical fluoride therapy in the past 2 yrs
using sugar free gums
No Results Posted