Trial | NCT02708628  Report issue

Title

The Efficacy of Extract of Allium Cepae, Allantoin and Heparin in Patients With Proven Scar Development
The Efficacy of Prophylactic Use of Extract of Allium Cepae, Allantoin and Heparin in Patients With Proven Scar Development After Excision of Previous Scar

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    120
To investigate the efficacy of prophylactic use of a topical gel containing extract of allium cepae, allantoin and heparin after surgical removal of the primary cesarean scar in the second cesarean section.
120 patients who are admitted for the second cesarean delivery, not taking prophylactic medication after the first cesarean section, whose scar development and measurements are taken will be included in the study. First caesarean section scars will be removed surgically for all patients. 60 out of 120 patients (treatment group) will use prophylactic topical scar gel 2 times in a day, and remaining 60 patients (control group )won't use. The efficacy of the drug will be evaluated by taking strict measurements of the incision and POSAS (The Patient and Observer Scar Assessment Scale) and Vancouver Scales at 6.12 and 24 weeks.

Steps;

Observation of the primary cesarean scar by taking scar measurements and using Vancouver and POSAS scales.
Surgical removal of the primary cesarean scar in the second cesarean section.
24 weeks topical application of gel containing extract of allium cepae, allantoin and heparin(only treatment group).
Observation of the skin incision at 6,12 and 24 weeks by taking scar measurements with using Vancouver and POSAS scales.
Study Started
Dec 31
2015
Primary Completion
Apr 30
2016
Study Completion
Oct 31
2016
Last Update
Oct 04
2016
Estimate

Drug extract of allium cepae, allantoin and heparin

prophylactic use of a topical gel containing extract of allium cepae, allantoin and heparin two times in a day after second c-section

  • Other names: Contractubex

Procedure Scar excision

Scar excision in second c-section

Patients using contractubex Active Comparator

Scar excision will be performed in second c-section for 60 patients and these patients will use prophylactic topical scar gel containing extract of allium cepae, allantoin and heparin two times in a day.

Patients not using contractubex Active Comparator

Scar excision will be performed in second c-section for 60 patients and these patients will not use prophylactic topical scar gel containing extract of allium cepae, allantoin and heparin.

Criteria 

Inclusion Criteria:

Patients who are admitted for the second cesarean delivery
Not to use topical scar gel after the first c-section

Exclusion Criteria:

chronic illness, immunosuppressive therapy or smoking
development of wound infection during the second c- section
allergies and hypersensitivities to components of the gel
No Results Posted