Trial | NCT02705885  Report issue

Title

IgY Efficacy on Periodontitis Patients
Evaluation of IgY Antibody Effectiveness in Supportive Therapy of Periodontitis Patients

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    60
Patients visiting National Hospital of Odonto-Stomatology for treating periodontitis used a food supplement (lozenge) containing chicken egg antibody (IgY) against Porphyromonas gingivalis gingipains as an adjunct to conventional scaling and root planing (SRP). After 8 weeks the patients were examined against. Parameters including probing depth (PD), bleeding on probing (BOP), number of P. gingivalis in periodontal pockets were evaluated and compared to the control group that had used placebo lozenges.
Study Started
Jun 30
2014
Primary Completion
Aug 31
2014
Study Completion
Mar 31
2015
Last Update
Mar 11
2016
Estimate

Dietary Supplement lozenges containing IgY

Patients consumed food supplement lozenges containing IgY after nonsurgical periodontal therapy

Dietary Supplement Placebo IgY

Placebo IgY

Gingipain IgY Experimental

Participants consume lozenges containing IgY against gingipains of Porphyromonas gingivalis

Placebo IgY Placebo Comparator

Participants consume lozenges containing placebo IgY

Criteria 

Inclusion Criteria:

patients diagnosed with chronic periodontitis
had at least 2 interproximal site with pocket depth between 3 mm to 5 mm
nonsmokers with at least 20 natural teeth
bone loss and bleeding on probing
had not undergone periodontal treatments within 6 weeks before the study

Exclusion Criteria:

patients received medication such as antibiotics or anti-inflammatory drugs within the previous 3 months
had allergy to egg proteins
No Results Posted