Title
Comparison of Ketoprofen Gel to Placebo in Mechanical Low Back Pain
Comparison of Ketoprofen Gel to Placebo in Patients Presented With Mechanical Low Back Pain to the Emergency Department: A Randomized Placebo Controlled Trial
Phase
Phase 4Lead Sponsor
Akdeniz UniversityStudy Type
InterventionalStatus
Unknown statusIndication/Condition
Low Back PainIntervention/Treatment
ketoprofen ...Study Participants
160Mechanical low back pain is one most important emergency department presentations of patients seeking pain relief. Although parenteral pain killers such as opioids, non-steroidal anti-inflamatuar drugs and paracetamol are used commonly in these patients, application of analgesics in gel forms might be an reasonable alternative to these drugs with fewer adverse effects.
Mechanical low back pain is one most important emergency department presentations of patients seeking pain relief. Parenteral pain killers such as opioids, non-steroidal anti-inflamatuar drugs (NSAID) and paracetamol are used commonly in these patients. However, these drugs are not out of adverse effects and can not be used in some patients with diverse comorbidities. Gel forms of NSAIDs are used commonly in the outpatient clinics and shown to be effective in these patients by a Cochrane meta-analysis. However, there is no data on the effect of gel forms of analgesics in ED. The application of analgesics in gel forms might be a reasonable alternative to the paranteral drugs with fewer adverse effects.
The present study aimed to reveal the effect of ketoprofen gel in patients presented with low back pain to emergency department.
2.5% ketoprofen gel (Fastjel) has been administer as 2 gr in 5 cm area.
Inclusion Criteria: Mechanical low back pain Exclusion Criteria: Under 18 years old Over 65 years old Pain less than 40 mm in visual analogue scale Allergy to the study drug Drug or alcohol addiction Pregnancy and lactation
