Trial | NCT02592122  Report issue

Title

Airway Responsiveness in Patients With AECOPD Mechanical Ventilation by Inspiratory and Bronchial Dilation Testchronic Obstructive Pulmonary Disease

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Unknown status

  • Intervention/Treatment

    albuterol ...

  • Study Participants

    120
In the patients with COPD mechanical ventilation, the bronchial dilatation is very common. However, the evaluation of the efficacy of the medical examination and other subjective indicators, such as doctors, depends on the doctor's experience; at present, there is no objective evaluation index. For patients with mechanical ventilation, the risk of cross infection can not only increase the risk of cross infection, but also increase the workload of clinical doctors and nurses. Therefore, this study proposes an objective evaluation method to evaluate the response of COPD patients to bronchial dilation. The hypothesis of this study can be used to guide the clinical medication through the test of the bronchus. If the patients with bronchial dilation test positive were used in the test, the patients were not used. In this evaluation method, the changes of airway resistance were measured by the accurate measurement of the patients with inhaled bronchial dilatation.
Study Started
Oct 31
2013
Primary Completion
Oct 31
2016
Anticipated
Last Update
Oct 30
2015
Estimate

Drug Salbutamol Aerosol

  • Other names: Ammonium bromide bromide aerosol

Drug No drugs

Atomization inhalation Active Comparator

First of all, investigators need to give patients to do the test, the result is more than 12% is positive group, less than 12% is negative group.Second, randomly selected into the atomization group

Without atomization inhalation Active Comparator

First of all, investigators need to give patients to do the test, the result is more than 12% is positive group, less than 12% is negative group.Secondly, the random selection is not the atomization group

Criteria 

Inclusion Criteria:

Acute exacerbation of chronic obstructive pulmonary disease
The mechanical ventilation time of the outdoor endotracheal intubation in the intensive care unit was less than 48 hours

Exclusion Criteria:

asthma
has received tracheotomy
long term mechanical ventilation (which has been accepted for more than 21 days).
severe pneumonia
Patients who cannot use a patient with bronchial dilation
there's a taboo on the use of a sedative.
refusal to participate in the study
48 hours to pull out the tube
No Results Posted