Trial | NCT02495064  Report issue

Title

Mometasone Furoate Cream Reduces Acute Radiation Dermatitis in Head and Neck Squamous Cell Carcinomas' Patients
Mometasone Furoate Cream Reduces Acute Radiation Dermatitis in Head and Neck Squamous Cell Carcinomas' Patients Receiving Radiation Therapy

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Unknown status

  • Intervention/Treatment

    mometasone ...

  • Study Participants

    160
Radiation dermatitis is an acute effect of radiation therapy,Especially in the neck skin of head and neck squamous cell carcinomas' patients.The investigators wanted to confirm the benefit of mometasone furoate (MF) in preventing acute radiation reactions, as shown in a previous study.
A randomized,self-comparative controlled trial was undertaken comparing MF cream with no cream administered from the first day of treatment for 5-6 weeks to prevent radiation dermatitis of neck during radiation therapy to the head and neck squamous cell carcinomas' Patients.

One side of patients' neck will begin to use MF cream from the first day of radiation therapy, while the other side accept no preventive measures.
Study Started
Jan 31
2015
Primary Completion
Dec 31
2016
Anticipated
Study Completion
Dec 31
2016
Anticipated
Last Update
Mar 09
2016
Estimate

Drug Mometasone Furoate Cream

One side of patients' neck will begain to use MF cream from the first day of radiation therapy.

  • Other names: Eloson

Mometasone Furoate Cream(MF) Experimental

participants will be given conventional Chemoradiotherapy and MF. MF Brief introduction: Generic name :Mometasone Furoate Cream. Dosage form:Each gram of Mometasone Furoate Cream contains mometasone furoate, USP in a cream base of hexylene glycol, phosphoric acid, propylene glycol stearate, stearyl alcohol and ceteareth-20, titanium dioxide, aluminum starch octenylsuccinate, white wax, white petrolatum, and purified water. Dosage:Apply a thin film of Mometasone Furoate Cream to the affected skin areas once daily during radiotherapy. It is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Chemoradiotherapy No Intervention

conventional Chemoradiotherapy only

Criteria 

Inclusion Criteria:

pathological diagnosis for head and neck squamous cell carcinomas and
going to have radiotherapy.

Exclusion Criteria:

pregnant,
lactating women,
infants,
elderly people with atrophy skin,
allergic constitution patients,
the corresponding parts of 5 radiotherapy skin ulceration or infection and
allergic patients to Mometasone Furoate Cream.
No Results Posted