Clinical Drug Experience Knowledgebase

Criteria

Inclusion Criteria:

Men and women ages 20 to 80 years
Individuals who are suffering from cancer-associated anorexia
Patients within 1 month after completion of chemotherapy
No plan for additional chemotherapy or radiotherapy
Anorexia visual analogue scale (VAS) ≥ 40/100mm
Qi deficiency scale ≥ 30 or Blood deficiency scale ≥ 30
Neutrophil ≥ 1,500/㎕, platelet ≥ 100,000/㎕
Total bilirubin lower than upper limit of normal (1.2 mg/㎗)
ALT, AST lower than 2-fold the upper limit of normal
Creatinine lower than 1.5 fold the upper limit of normal(1.09 mg/㎗)
Written informed consent for participation in the trial

Exclusion Criteria:

Patient impossible to oral intake
Patient 5 years after cancer diagnosis
ECOG performance status score > 3
Patient with dementia, delirium, depression
Patient who complain of more than 7 points when we use Numeric Rating Scale, which can affect appetite or calorie intake, within 2 weeks of screening
Patient with diseases which can influence on appetite (such as hypoadrenalism, etc)
Patient who are taking appetizers (such as megestrol acetate, corticosteroids, thalidomide)
Women who has possibility of a pregnancy
Others who are judged not to be appropriate to study