Trial | NCT02413658  Report issue

Official Title

Phenytoin in the Healing of Clean Surgical Wounds

  • Phase

    Phase 2

  • Study Type

    Interventional

  • Status

    Unknown status

  • Intervention/Treatment

    phenytoin ...

  • Study Participants

    100
The purpose of this study is to investigate the potential healing properties of phenytoin.

The investigators will use the donor site of a split skin thickness graft (SSTG) to model a basic wound in a randomized controlled trial of topical phenytoin against current best clinical practice. The investigators aim to demonstrate a dose dependent effect. The investigators hypothesis, based on previous clinical experience at our center and on current available literature, that phenytoin will reduce wound healing time.
Study Started
Mar 31
2015
Primary Completion
Apr 30
2016
Anticipated
Last Update
Apr 10
2015
Estimate

Drug Phenytoin

Topical use of phenytoin solution on dressings of split thickness skin graft sites.

  • Other names: Dilantin, Dilantin-125

Drug Sugar solution

Control Active Comparator

Dressings of best current clinical practice, sugar solution.

Phenytoin 1 Experimental

Dressings using phenytoin solution 20mg/ml

Phenytoin 2 Experimental

Dressings using phenytoin solution 40mg/ml

Criteria 

Inclusion Criteria:

Undergoing split thickness skin graft during trial time period at Children's Surgical Centre

Exclusion Criteria:
No Results Posted