Trial | NCT02309424  Report issue

Title

The Effect of Vinegar on Glucose and Lipid Metabolism in Subjects With Impaired Glucose Tolerance or Type 2 Diabetes
The Effect of Vinegar on Glucose and Lipid Metabolism in Peripheral Tissues in Subjects With Impaired Glucose Tolerance or Type 2 Diabetes

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    vinegar ...

  • Study Participants

    20
This open, randomized, cross-over, placebo-controlled study aims to investigate the effects of vinegar on glucose metabolism, endothelial function and circulating lipid levels in subjects with impaired glucose tolerance or type 2 diabetes, using the arteriovenous difference technique.
Subjects with IGT or type 2 diabetes will be randomised to consume 20ml vinegar (6% acetic acid) or placebo before a mixed meal. Plasma samples will be taken for 300min from the radial artery and from a forearm vein for measurements of glucose, insulin, triglycerides, non-esterified fatty acids (NEFA) and glycerol. Muscle blood flow will be measured with strain-gauge plethysmography. Glucose flux will be calculated as the arteriovenous difference of glucose multiplied by the blood flow rates.
Study Started
Jul 31
2008
Primary Completion
Dec 31
2013
Study Completion
Dec 31
2014
Last Update
Dec 05
2014
Estimate

Dietary Supplement Vinegar

0,50mmol vinegar (6% acetic acid)

Other Placebo

50 ml water

Vinegar Active Comparator

0,50mmol vinegar (6% acetic acid)

Placebo Placebo Comparator

50 ml water

Criteria 

Inclusion Criteria:

Subjects with impaired glucose tolerance or newly diagnosed type 2 diabetes before the initiation of medication therapy
Recreationally active
With stable body weight and diet during the last two months.

Exclusion Criteria:

Any systemic disease (besides glucose abnormalities)
Any medication therapy
Diabetic complications
No Results Posted