Title
Study of Interventional Pulmonologic Treatment of Benign Central Airway Fibrotic Stricture
Prospective, Randomized, Open, Controlled, Multicenter Stucy of Interventional Pulmonologic Treatment of Benign Central Airway Fibrotic Stricture
Phase
N/ALead Sponsor
People's Liberation Army of ChinaStudy Type
InterventionalStatus
Unknown statusIndication/Condition
Obstructive Airway DiseaseIntervention/Treatment
mitomycin ...Study Participants
160The purpose of this study is to evaluate the efficacy and safety of four interventional pulmonology techniques for the treatment of fibrotic central airway stricture.
The four techniques are：
balloon dilation
balloon dilation plus cryotherapy
balloon dilation plus spiculiform electrosurgery
balloon dilation plus mitomycin C injection
give the cases balloon dilation as the intervention
give the cases balloon dilation plus cryotherapy as the intervention
give the cases balloon dilation plus spiculiform electrosurgery as the intervention
give the cases Balloon dilation plus mitomycin C as the intervention
Inclusion Criteria: tracheal incision,intubation or bronchial tuberculosis caused central airway fibrotic stenosis the degree of stenosis is above 50% estimated survival duration is longer than 3 months recieved no treatment one month before can understand the statement informed consent agree to enroll in the study Exclusion Criteria: older than 70 years or younger than 18 years not fibrotic stenosis not central airway stenosis existence of lumina collapse or twisting severe arrhythmia, myocardial ischemia or hypertensive crisis coagulation disorders existence of severe organ disfunction allergic to anesthesia drugs refuse to participate the study
