Title
Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia
Is Continuous Wound Infusion With Ropivacaine Better Than Intrathecal Morphine for Post-caesarean Analgesia? A Prospective, Randomized, Controlled, Double Blinded Study
Phase
Phase 3Lead Sponsor
Brugmann University HospitalStudy Type
InterventionalStatus
Completed Results PostedIndication/Condition
Post Caesarean AnalgesiaIntervention/Treatment
ropivacaine morphine ...Study Participants
192The aim of this study is to compare effective analgesia with continuous wound infiltration of ropivacaine through multi-holed catheter or with morphine 100 mcg added intrathecally to spinal anesthesia, after elective Caesarean delivery.
Double blind, 3 groups
Control group: Rachi 0,1 ml saline, Infusion 300ml saline
Group rachi-morphine: 0,1ml =100µg morphine/300ml saline
Group KT: 0,1 ml saline/300 ml naropin 0.2%
wound infiltration
100 µg added to the spinal anaesthesia
placebo in spinal anaesthesia and in wound infiltration
ropivacaine 2 mg/ml bolus 15 ml continuous 10 ml/h wound infusion and intrathecal saline
100 µg intrathecal morphine and saline infiltration
Inclusion Criteria: Patients aged 18 years and more, ASA 1 or ASA 2, pregnant with at least 34 weeks of gestational age, admitted for a planned caesarian with a Pfannenstiel incision and having signed the informed consent form. Exclusion Criteria: Refusal of the patient or contra-indication to locoregional anesthesia Allergy to the products used ASA 3 ASA 4 Sleep apnea syndrome and/or obesity (BMI > 35) Size inferior to 155cm existence of a language barrier
| Event Type | Organ System | Event Term | Ropivacaine Infiltration | Rachi Morphine | Placebo |
|---|
T0 until first request of morphine PCAIV
Morphine consumption with PCAIV
Is there a decrease of the incidence of morphine side effects such as nausea, vomiting, pruritus?
Outcome Measure Data Not Reported
