Trial | NCT02162966  Report issue

Title

Safety and Efficacy Study of High Dose Colistin
Use Of High Dose Colistin in Multi Drug Resistant Gram Negative Infections in Critically Ill Adult Patients. Randomized Controlled Clinical Trial

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Unknown status

  • Intervention/Treatment

    colistin ...

  • Study Participants

    330
Colistin is a rapidly acting bactericidal antimicrobial agent that possesses a post antibiotic effect against MDRO Gram-negative bacteria, such as as Pseudomonas aeruginosa, Acinetobacterbaumannii, and Klebsiella pneumonia.
Study Started
May 31
2014
Primary Completion
Oct 31
2016
Anticipated
Study Completion
Oct 31
2016
Anticipated
Last Update
Apr 01
2015
Estimate

Drug High Dose Colistin

High Dose Colistin

  • Other names: colistin

Drug Standard Dose Colistin

Standard Dose Colistin

  • Other names: Colistin

High Dose Colistin Experimental

High dose colistin protocol

Standard Dose Colistin Active Comparator

Standard dose of colistin

Criteria 

Inclusion Criteria:

Patient age more than or equal 18 years old.
Patient has clinical signs and symptoms of infection with suspected or proven infection due to Carbapenem resistant microorganism.
Patient was started with Empirical therapy of Colistin and positive MDRO within 5 days of empirical therapy.

Exclusion Criteria:

Patient age less than 18 years.
Pregnant patient.
If received Colistin treatment for less than 72 hours.
Renal Replacement Therapy.
No Results Posted