Trial | NCT02046499  Report issue

Official Title

A Randomized Trial Comparing Oxytocin and Oxytocin + Ergometrine for Prevention of Postpartum Haemorrhage at Caesarean Section

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    oxytocin ...

  • Study Participants

    540
This is a randomized trial comparing oxytocin versus oxytocin + syntometrine in the prevention of post partum haemorrhage in patients undergoing caesarean section
Study Started
Jan 01
2014
Primary Completion
Jun 30
2014
Study Completion
Sep 30
2014
Last Update
Mar 09
2021

Drug Oxytocin

Oxytocin will be administered intravenously as per standard protocol

Drug Oxytocin ergometrine

Oxytocin ergometrine will be administered intra-musculalry

  • Other names: Syntometrine

Oxytocin arm Active Comparator

Oxytocin alone administered which is current standard of care

Oxytocin + syntometrine Experimental

Oxytocin plus syntometrine administered

Criteria 

Inclusion Criteria:

Pregnant women delivering by caesarean section older than 18 years willing and able to give informed consent

Exclusion Criteria:

• Women not willing or women not able to provide consent

Women who have a classical caesarean section
Women younger than 18 years of age
Women with any of the following conditions will be excluded (ergometrine contra-indicated in patients with these conditions).
Pre- eclampsia
Eclampsia,
Uncontrolled hypertension (hypertension defined as systolic blood pressure more than 140 mm Hg and diastolic blood pressure more than 90 mm Hg)
Any cardiac lesion
Impaired liver function
Impaired kidney function
Hypersensitivity to any of the active ingredients of the preparations that will be used (Syntometrine® or Syntocinon®)
Occlusive vascular disease
Autoimmune vasculitis
No Results Posted