Clinical Drug Experience Knowledgebase

Criteria

Inclusion Criteria:

20 years and older
Person who agreed to participate in this study and signed voluntarily on the written informed consent form
Person who is confirmed as colorectal cancer through histological and image diagnosis and scheduled for adjuvant or palliative therapy with mFOLFOX-6 regimen
Fertile patients with negative pregnancy test confirmed and who has agreed to use effective contraception
Person who is able to fully communicate with the physician about his/her fatigue status and is able to completely fill out the questionnaires
Life expectancy more than 6 months
Performance status of ECOG grade 0~1
Hb ≥ 9g/dL
Person with moderate liver function (AST, ALT ≤ 2.5 × ULN)
Person with moderate renal function (Cr ≤ 1.5 × ULN)

Exclusion Criteria:

Pregnant or nursing women
Primary brain cancer, brain metastases or other CNS malignancy, including CNS lymphoma
No controlled pain despite the use if analgesics.
Person showing hypothyroidism despite the hormone treatment
Person with insomnia despite an appropriate treatment
No controlled hypertension (DBP >100mmHg or SBP >160mmHg)
Person who has experience of hypersensitivity to the trial drug (ginseng) components
Person with autoimmune disorders (Multiple sclerosis, Lupus, rheumarthritis etc.)
Person who is alcoholic dependent or has psychiatric disorder
Person who has cognitive or psychiatric problems
Person who has an experience of chemotherapy agents use 6 months before a screening visit
Person who had a surgery 2 weeks before a screening visit
Person who had taken herbal medicinal product (including Chinese medicine) 4 weeks before the screening visit
Person who has medical status that is judged to affect the result or who is judged as inappropriate for the study by the physician