Title
Injection of Hormone to Enhance Implantation in Embryo Transfer After IVF
Intrauterine Injection of Human Chorionic Gonadotropin to Enhance Embryo Implantation
Phase
N/ALead Sponsor
Servy Massey Fertility InsitituteStudy Type
InterventionalStatus
Completed No Results PostedIndication/Condition
InfertilityIntervention/Treatment
human choriogonadotropin alfa ...Study Participants
75The endometrium is deprived of signals form the embryo in IVF conditions. Studies suggest that placing HCG into the uterus prior to embryo transfer can enhance implantation.
The study is in pilot phase, uncontrolled. The risks appear to be minimal and there are conflicting new reports being announced.
A small amount of fluid with HCG is injected into the uterus. HCG is a potent signal to the uterus for preparation for implantation.
This is not a funded study. Three published studies suggest the approach is valid; one refutes the concept.
must have good blastocysts
phase 1 non randomized pilot
Inclusion Criteria: - infertility patients undergoing IVF with good expectation of two embryos day 3 or day 5. must speak and read English. Includes donor eggs. Exclusion Criteria:abnormal uterus -