Trial | NCT01954186  Report issue

Official Title

When and How to Administer Oxytocin for Active Management of Third Stage of Labour

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    oxytocin ...

  • Study Participants

    600
To compare the efficacy of the route and timing of oxytocin administration for Active management of third stage of labour (AMTSL).
Our objective is to determine the most efficient route and timing of oxytocin administration by measuring the duration of third stage of labour, quantitative blood during the first hour after delivery and comparing haemoglobin and haematocrit changes and the need for additional interventions in patients who had either a spontaneous labour or received labour augmentation with oxytocin.
Study Started
Jan 31
2010
Primary Completion
Oct 31
2010
Study Completion
Dec 31
2010
Last Update
Oct 01
2013
Estimate

Drug intravenous & intramuscular oxytocin

intravenous or intramuscular 10 iu oxytocin

  • Other names: Postuitrin

Procedure after delivery of the fetus & when anterior shoulder seen

oxytocin 10 iu after the delivery of the fetus or when the anterior shoulder was seen after the fetal head was delivered

intravenous & intramuscular oxytocin Experimental

intravenous or intramuscular 10 iu oxytocin

after delivery & when anterior shoulder seen Active Comparator

oxytocin 10 iu after the delivery of the fetus or when the anterior shoulder was seen after the fetal head was delivered

Criteria 

Inclusion Criteria:

having a singleton pregnancy above 37th gestational week
normal live vaginal delivery with cephalic presentation
being in active labor

Exclusion Criteria:

Fetal demise
multiple pregnancy
known coagulation disorder
presentation anomalies
placental pathology
liver disease
thrombocytopenia
hypertension or being currently on anticoagulants
having a cesarean section, operative delivery or deep vaginal tear
chorioamnionitis
developing HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count) or DIC (disseminated intravascular coagulation) before delivery
No Results Posted