Clinical Drug Experience Knowledgebase

Criteria

Inclusion Criteria:

Age≥18 years at screening.
Patients who have ischemia myocardial symptoms and whose clinical symptoms keep stable for at least one month.
Have at least one of the following events (providing hospital records or inspection report): 1)history of acute myocardial infarction for at least half of a year; 2) history of PCI or CABG for at least half of a year; 3) coronary CT angiography or coronary angiography shows that at least one of the main branches of coronary artery stenosis is no less than 50%.
Provide informed consent form.

Exclusion Criteria:

History of acute myocardial infarction, vascular reconstruction, CABG or PCI within half of a year.
Prepared to undertake CABG or PCI during this study.
Serious cardiovascular diseases: sustained severe angina (CCS Ⅳ), refractory heart failure, cardiogenic shock, severe aortic stenosis or aortic insufficiency.
Severe respiratory diseases;
Diabetic patients with poor glycemic control (fasting blood glucose > 200 mg/dl or 11.1mmol/L for more than twice within one month before the study entry).
Hypertensive patients with poor control of blood pressure, systolic pressure≥180mmHg or diastolic pressure≥110mmHg before entry.
Severe liver and kidney diseases,such as active liver disease, cirrhosis and uremia.
Any other severe diseases, such as malignant tumor, severe anemia and severe renal artery stenosis.
Unable or unwilling to sign informed consent form.
Join another trial or has received random allocation of this study within one month before entry.
Pregnant or who were attempting to become pregnant.
Patients who are regarded as not being suitable participants by the study investigators.