Official Title
Bioavailability of Potassium From Potatoes and Potassium Gluconate
Phase
N/ALead Sponsor
Purdue UniversityStudy Type
InterventionalStatus
Completed No Results PostedIndication/Condition
Potassium Bioavailability Blood PressureIntervention/Treatment
potato potassium gluconate ...Study Participants
45This study is designed to compare the effect of sources of potassium on uptake and the effect of potassium on blood pressure.
The study will compare uptake of potassium from three different doses and sources; supplements (720, 1440 and 2160 mg) potatoes (720, 1440 and 2160 mg) or French fries (2160 mg).
During 9 phases, participants will consume a controlled diet with the supplements, potato or french fries (every other week for 5 days). On the 4th day, blood and urine samples will be taken to monitor potassium uptake and excretion. Measures of blood pressure will be analyzed at defined time points throughout the intervention.
Subjects will consume tablets containing no potassium in addition to a basal diet containing 2336 mg potassium
Subjects will consume 720 mg potassium in the form of potassium gluconate tablets daily in addition to a basal diet containing 2336 mg potassium
Subjects will consume 1440 mg potassium in the form of potassium gluconate tablets daily in addition to a basal diet containing 2336 mg potassium
Subjects will consume 2160 mg potassium in the form of potassium gluconate tablets daily in addition to a basal diet containing 2336 mg potassium
Subjects will consume 720 mg potassium in the form of potato daily in addition to a basal diet containing 2336 mg potassium
Subjects will consume 1440 mg potassium in the form of potato daily in addition to a basal diet containing 2336 mg potassium
Subjects will consume 2160 mg potassium in the form of potato daily in addition to a basal diet containing 2336 mg potassium
Subjects will consume 2160 mg potassium in the form of french fries daily in addition to a basal diet containing 2336 mg potassium
Subjects will consume a basal diet containing 2336 mg potassium daily
Inclusion Criteria: Able to adhere to the visit schedule, protocol requirements and available to complete the study Normotensive men and women Aged 20-60 years BMI of 15-35 Exclusion Criteria: Medication to treat hypertension or hypotension Medication known to affect electrolyte metabolism or contain high levels of potassium or sodium smoke cigarettes or use illegal drugs Hypertension or hypotension Diseases known to affect potassium metabolism Pregnant Allergic to nuts
