Trial | NCT01812564  Report issue

Title

Use of Platelet Rich Plasma in the Management of Acute Hamstring Muscle Strain Injury
Clinical Utilization of Growth Factors Preparations in the Management of Acute Hamstring Muscle Strain Injury

  • Phase

    Phase 2

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    platelet poor plasma ...

  • Study Participants

    90
The purpose of this study is to evaluate the therapeutic benefit of utilizing complex growth factor preparations (Platelet Rich Plasma (PRP) in the management of acute hamstring injuries.

The hypothesis is that the time to return to sport is shorter in the patient group treated with Complex Growth Factor Preparations (PRP) in combination with exercise therapy in comparison with 2 control groups:

the patient group treated with Platelet Poor Plasma (PPP) injections in combination with exercise therapy (control injection AND usual care).
the patient group treated with exercise therapy (usual care)
Study Started
Nov 30
2009
Primary Completion
Oct 31
2013
Study Completion
Oct 31
2014
Last Update
Jan 14
2015
Estimate

Biological Platelet Poor Plasma (PPP)

Biological Platelet Rich Plasma (PRP)

PPP Placebo Comparator

Placebo: Platelet Poor Plasma Under sterile conditions, patients will receive under ultrasound guidance 3 times, 1 cc injection of PPP each, administered by a sports medicine physician (total 3 cc PPP). Following the completion of the injections (treatment or control) physiotherapy will commence. Physiotherapy protocols will be based on current ASPETAR best practice models (usual care)

PRP Active Comparator

Biological: Platelet Rich Plasma Under sterile ultrasound conditions, patients will receive under ultrasound guidance 3 times, 1 cc injection of PRP each, administered by a sports medicine physician (total 3 cc PRP). Following the completion of the injections (treatment or control) physiotherapy will commence. Physiotherapy protocols will be based on current ASPETAR best practice models (usual care)

Physiotherapy No Intervention

These patients will not receive an injection. Following the inclusion physiotherapy will commence. Physiotherapy protocols will be based on current ASPETAR best practice models (usual care)

Criteria 

Inclusion Criteria:

Acute onset posterior thigh pain
MRI confirmed Grade I, II hamstring lesions
< 5 days from injury
Able to perform Physiotherapy at ASPETAR (5 sessions/week)
Available for follow-up
Male
Age > 18 years

Exclusion Criteria:

Diabetes, immuno-compromised state
Overlying skin infection
Re-injury or Chronic ongoing hamstring injury
Unwilling to comply with follow up
Contraindication to MRI
Needle Phobia
Bleeding disorder or other medical contraindication to injection
Medication increasing bleeding risk (e.g. Plavix)
Concurrent other injury inhibiting rehabilitation
No Results Posted