Trial | NCT01806454  Report issue

Title

Calcium Supplementation to Prevent Preeclampsia in Sichuan Province of China
Calcium Supplementation to Prevent Preeclampsia in Sichuan Province of China: a Multi-center, Prospective Random Trial

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Unknown status

  • Intervention/Treatment

    calcium ...

  • Study Participants

    11000
the purpose of this study is to determine whether calcium supplementation is effective to prevent preeclampsia in Sichuang Province of china and which dose is more suitable
Study Started
Oct 31
2013
Primary Completion
Nov 30
2015
Anticipated
Last Update
Aug 25
2015
Estimate

Drug calcium

calcium A Active Comparator

tablets, 600mg per day,till birth

calcium B Active Comparator

tablets,1200mg per day,till birth

Criteria 

Inclusion Criteria:

Nulliparity;age ≥35 years;Previous pre-eclampsia;Family history of pre-eclampsia;Multiple pregnancy;Time between pregnancies ≥10years;Body mass index ≥25;diastolic pressure ≥ 80 mm Hg before 20 weeks' gestation;Proteinuria ≥+ on more than one occasion or ≥ 300 mg/24 h before 20 weeks' gestation;Underlying medical conditions(Pre-existing hypertension;Pre-existing renal disease;Pre-existing diabetes;Presence of antiphospholipid antibodies;Chronic autoimmune disease);male sex partner's predecessor wife has Previous pre-eclampsia

Exclusion Criteria:

first prenatal visit after 16 weeks' gestation;severe anemia;other Underlying medical conditions which need treatment first (such as uncontrolled hyperthyreosis )
No Results Posted