Official Title
Methadone in Post-Herpetic Neuralgia Pain
Phase
Phase 3Lead Sponsor
University of Sao PauloStudy Type
InterventionalStatus
Completed No Results PostedIndication/Condition
Post-herpetic NeuralgiaIntervention/Treatment
methadone ...Study Participants
10Neuropathic pain is a common condition and affecting 40 to 70% of the general population. Post-herpetic neuralgia is a condition almost complex and requires a multi modal treatment. Aim: This is a pilot proof-of-principle study designed to evaluate the use of low-dose methadone in post-herpetic neuralgia patients who remained refractory after first and second line treatment for post-herpetic neuralgia (PHN) and had indication for the association of an opioid agent to their current drug regimen.
patients with post-herpetic neuralgia take methadone or placebo to treat pain symptoms.
patients with post-herpetic neuralgia take placebo to treat the pain symptoms.
Inclusion Criteria: Patients with chronic (>6 months) symptomatic PHN with visual analogical scale >40/100mm use of first and second line drugs (tricyclic antidepressants, venlafaxine and gabapentinoids) Exclusion Criteria: Don't full the criteria above