Trial | NCT01719133  Report issue

Title

Skin Prick Tests With AllerT in Subjects Allergic to Birch Pollen
Détermination de la réactivité cutanée de Volontaires Allergiques au Pollen de Bouleau Contre Des Peptides dérivés de Bet v 1

  • Phase

    Phase 1

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    birch allergen ...

  • Study Participants

    20
Assessment of skin reactivity by skin prick tests to synthetic peptides derived from the major birch allergen bet v 1, in subjects allergic to birch pollen.
The study tested - all by skin tests - in the same group of 20 trial subjects, one positive control (histamine solution), one negative control (placebo saline) and five experimental peptides called T1, T2, T3, T4 and T5. Results of the skin prick tests were scored as negative (no reaction) or positive (wheal diameter > 4 mm with erythema)
Study Started
Feb 29
2008
Primary Completion
Mar 31
2008
Study Completion
Jun 30
2008
Last Update
Nov 01
2012
Estimate

Drug placebo

saline solution

  • Other names: saline

Drug Histamine

positive control

  • Other names: Histamine solution

Drug AllerT1

synthetic peptide T1

Drug AllerT2

synthetic peptide T2

Drug AllerT3

synthetic peptide T3

Drug AllerT4

synthetic peptide T4

Drug AllerT5

synthetic peptide T5

Drug mix of AllerT1-T2-T3

mix of peptides T1, T2 and T3

  • Other names: AllerT

Drug mix of AllerT4-T5

mix T4-T5

  • Other names: mix T4-T5

All subjects Other

placebo histamine T1 T2 T3 T4 T5 T1-T2-T3 T4-T5

Criteria 

Inclusion Criteria:

history of allergy symptoms during previous birch pollen season
positive skin prick test to birch pollen extract

Exclusion Criteria:

pregnancy
uncontrolled asthma
other significant clinical conditions or immune disorders
subjects taking antihistamines or drugs with antihistamine activity
No Results Posted