Trial | NCT01682889  Report issue

Title

The Effect of High Dose Arginine Infusion on Hemodynamic and Peripheral Microcirculation
The Effect of High Dose Arginine Infusion on Hemodynamic and Peripheral Microcirculation: a Randomized, Controlled Clinical Trial in Patients Receiving Peripheral Vascular Surgery

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    arginine ...

  • Study Participants

    40
The aim of this study was to investigate the effect of a 24- hrs L-arginine infusion on hemodynamic and on parameters of microcirculation in patients with peripheral arterial occlusive disease (PAOD).
Study Started
Jan 31
2007
Primary Completion
Dec 31
2008
Study Completion
Jan 31
2012
Last Update
Sep 11
2012
Estimate

Dietary Supplement Arginine

L-arginine-hydrochlorid (0.35 g/kg body weight) intravenously for 24 hours

Dietary Supplement Placebo

NaCl 0.9% intravenously for 24h

Placebo Placebo Comparator

NaCl 0.9% intravenously for 24 hours after induction of anaesthesia

Arginine Active Comparator

L-arginine-hydrochlorid (0.35 g/kg body weight) intravenously for 24 hours after induction of anaesthesia

Criteria 

Inclusion Criteria:

female or male patients receiving peripheral bypass surgery
age between 55 and 75 years

Exclusion Criteria:

metabolic acidosis
No Results Posted