Trial | NCT01631305  Report issue

Title

Levothyroxine for Children With Euthyroid Sick Syndrome
Efficacy and Safety of Levothyroxine in Critical Children With Euthyroid Sick Syndrome in a Pediatric Intensive Care Unit.

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    80
The purpose of this study is to determine whether levothyroxine is effective and safe in the treatment of children with euthyroid sick syndrome, hospitalized in a pediatric intensive care unit.
Children with euthyroid sick syndrome, hospitalized in a pediatric intensive care unit, will be randomised to receive either Levothyroxine or placebo, to determine if it diminishes mortality.
Study Started
Jan 31
2012
Primary Completion
Dec 31
2013
Study Completion
Dec 31
2013
Last Update
Mar 05
2014
Estimate

Drug Levothyroxine

3 mcg/kg/day

  • Other names: Brand: Eutirox.

Other Calcium magnesia

Placebo.

Levothyroxine Experimental

3 mcg/kg/day

Control Placebo Comparator

Calcium magnesia.

Criteria 

Inclusion Criteria:

All children aged 1 month to 17 years.
Admitted to pediatric intensive care unit.
TSH and thyroid hormones below age specific levels.

Exclusion Criteria:

Known thyroid condition.
Brain death.
Gut conditions that contraindicate oral route.
Readmissions to intensive care unit.
No Results Posted