Trial | NCT01612130  Report issue

Title

Valerian for Conscious Sedation in Patients Submitted to Impacted Lower Third Molars Surgery
Valeriana Officinalis L. for Conscious Sedation in Patients Submitted to Impacted Lower Third Molars Surgery: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    20
The aim of the present study was to evaluate the efficacy of Valeriana officinalis L. 100 mg in single oral doses one hour preoperative as conscious sedation during the impacted lower third molar surgery.
Evaluate the efficacy of Valeriana officinalis L. (Valerian) for control of anxiety during third molar surgery. Study design: A single oral dose of either valerian (100 mg) or placebo was randomly administered one hour before each surgical procedure to 20 volunteers between 17 and 31 years of age. Anxiety level was assessed through questionnaires, physiological parameters (blood pressure and heart rate) and the observation of signs.
Study Started
Mar 31
2003
Primary Completion
Aug 31
2003
Study Completion
Aug 31
2003
Last Update
Jun 06
2012
Estimate

Drug 100 mg of Valeriana officinalis L

A single dose of 100 mg of Valeriana officinalis L., 1 hour prior to surgical procedures

  • Other names: Valerian

Drug Placebo 100mg

A single dose of 100 mg of placebo orally, 1 hour prior to surgical procedures

Valeriana officinalis L (100mg) Experimental

100 mg of Valeriana officinalis L. (Valerian)

Placebo (100 mg) Placebo Comparator

Placebo 100mg

Criteria 

Inclusion Criteria:

Indication for bilateral extraction of asymptomatic impacted mandibular third molars in similar positions based on the Pell & Gregory classification

Exclusion Criteria:

Use of any type of medication in the 15 days prior to the onset of the study; history of hypersensitivity to the drugs, substances or materials employed in the experiment; pregnancy or lactation
No Results Posted