Trial | NCT01400048  Report issue

Title

Aloe Vera in Irritable Bowel Syndrome
Aloe Vera Versus Placebo for Patients With Irritable Bowel Syndrome

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    aloe vera ...

  • Study Participants

    173
The purpose of the present study is to study the effect of aloe vera in the treatment of IBS patients in a randomized, double-blind placebo controlled study.
There is limited knowledge of the IBS pathophysiology, absence of biological markers and therefore few effective treatment options. IBS therefore contributes to difficulties in the management of the patients. Aloe vera has a long association with herbal medicine, from the Ebers Papyrus from 16th century BCE. It is alleged to be effective in treatment of wounds, to improve blood glucose levels in diabetics, and it may reduce symptoms and inflammation in patients with ulcerative colitis. Evidence of the effects of aloe vera in the treatment of IBS, is however limited and contradictory.
Study Started
Jan 31
2010
Primary Completion
Dec 31
2016
Study Completion
Mar 31
2017
Last Update
Sep 10
2018

Dietary Supplement Aloe vera effervescent tablet (AVH200)

250 mg aloe vera and 60 mg ascorbic acid, Aloe Life®

Dietary Supplement Placebo control

60mg Ascorbic acid

Aloe vera effervescent tablet (AVH200) Active Comparator

Placebo Placebo Comparator

Criteria 

Inclusion Criteria:

IBS according to the Rome III criteria
Adults

Exclusion Criteria:

other GI disorders
other medical conditions
were pregnancy or breast-feeding
food allergy or intolerance to other than lactose
ongoing intake of aloe vera products
No Results Posted