Official Title
Nasal Packing as a Drug Delivery System Postoperatively in Chronic Sinusitis With Polyposis
Phase
Phase 3Lead Sponsor
University of MichiganStudy Type
InterventionalStatus
Completed Results PostedIndication/Condition
Chronic Sinusitis PolyposisIntervention/Treatment
budesonide ...Study Participants
23That high-dose steroid applied to the nasal cavity immediately post-operatively will improve olfaction and healing following endoscopic sinus surgery.
applied to nasal packing after surgery
each subject serves as their own control with one nostril being treated with pulmicort and one not
Inclusion Criteria: hyposmia and nasal obstruction for >12 weeks bilateral nasal polyposis candidate for surgery Exclusion Criteria: immunocompromised non-English speaking prisoner pregnant/lactating will not attend follow up appointments
| Event Type | Organ System | Event Term |
|---|
will be measured with the University of Pennsylvania Smell Identification Test (UPSIT), whose scores range from 0 to 40, where 0 is the inability to smell anything and 40 is perfect smell identification
will be assessed with the Perioperative Sinus Endoscopy score (POSE), a 20 point scale where 0 is no sinus challenges and 20 represents the greatest blockage.
Scored with the University of Pennsylvania Smell Identification Test, whose scores range from 0 to 40, where 0 is the inability to smell anything and 40 is perfect smell identification
Assessed with Perioperative Sinus Endoscopy (POSE) score
