Trial | NCT01142960  Report issue

Official Title

Effects of Lycium Barbarum Supplements on the Progression of Senile Cataract in Hong Kong Chinese Population

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    238
With the rapid growing aging population, age-related eye diseases including cataract are becoming more prevalent. The demand for cataract surgery and post-surgical care posed enormous financial burdens to the government.

Lycium barbarum contains lutein and zeaxanthin which can filter the phototoxic blue light and neutralize the reactive oxygen species, thus provide a protective effect against cataract formation.

This study aims to determine the effects of Lycium barbarum Supplements on the progression of senile cataract in Hong Kong Chinese elderly.
Please note that a manuscript for this study is being prepared. Detailed description will be provided after we come up with the final draft.
Study Started
Nov 30
2009
Primary Completion
Apr 30
2012
Study Completion
Jun 30
2012
Last Update
May 12
2016
Estimate

Dietary Supplement Starch

1350mg/day

Dietary Supplement Lycium Barbarum

1350mg/day

Placebo Active Comparator

Starch

Lycium Barbarum Experimental

Lycium Barbarum supplement

Criteria 

Inclusion Criteria:

Unlikely to have cataract surgery within 3 years
Presence of mild to moderate cataract in one or both eyes, graded by Lens Opacities Classification System III (LOCSIII).
logMAR acuity equivalent to Snellen acuity of 20/63 or better
no previous history and clinical signs of glaucoma by determining intraocular pressure using applanation Tonometry (no more than 22mmHg)
no ocular anomalies: amblyopia, binocular anomalies, ocular trauma
no history of eye surgery, laser treatment, iritis, retinal crystalline deposits, macular degeneration, or optic nerve diseases
no extended use of systemic or ocular corticosteroid drugs
no concurrent participation of other systemic or ocular drug intervention study

Exclusion Criteria:

diabetes mellitus
renal failure
fat malabsorption syndrome
intestinal surgery history
chronic diarrhea
alcoholism
use of anticoagulants
regular use of nutritional supplements such as multi-vitamin, mineral and other antioxidant supplements (including Omega-3)
No Results Posted