Trial | NCT01084824  Report issue

Title

A Trial Examining the Treatment of Common Warts With Combination Liquid Nitrogen (LN2) and Cantharidin
A Randomized Clinical Trial Examining the Efficacy of Treatment of Cutaneous Verruca Vulgaris in Adult Patients With Combined Liquid Nitrogen Cryotherapy and Topically Applied Cantharidin

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Study Participants

    70
The purpose of the study was to see if liquid nitrogen, a commonly used treatment for warts, is more effective if it is used alone, or if it is more effective if combined with cantharidin, a topical treatment also commonly used for warts (verruca vulgaris).
Study Started
Jun 30
2007
Primary Completion
Jun 30
2008
Study Completion
Sep 30
2008
Last Update
Mar 11
2010
Estimate

Drug Liquid nitrogen and cantharidin

Liquid nitrogen applied to wart(s), then cantharidin 1% topical applied afterward.

Drug Liquid nitrogen and topical placebo

Liquid nitrogen applied to wart(s), then placebo vehicle applied thereafter.

Liquid nitrogen and canthardin Active Comparator

Liquid nitrogen applied to wart(s), then cantharidin 1% topical applied afterwards.

Liquid nitrogen and placebo Placebo Comparator

Liquid nitrogen applied to wart(s) then placebo vehicle afterwards.

Criteria 

Inclusion Criteria:

common warts on non-genital, non-facial skin
otherwise healthy
between 18-65 and able to give informed consent
capable of tolerating treatment

Exclusion Criteria:

Ill-health
Poor tolerance or sensitivity to treatments in study
<18 years old; >65 years old
verruca plana or condyloma acuminata
immunosuppression or immune dysfunction
significant peripheral vascular disease
significant sensitivity to cold
epidermodysplasia verruciformis
mosaiform warts or periungual warts
No Results Posted