Trial | NCT00960830  Report issue

Title

Mirtazapine Reduces ICD Shocks in ICD Patients With Depression and Anxiety
Mirtazapine Reduces ICD Appropriate Shocks in Cardioverter Implanted Patients With Depression and Anxiety

  • Phase

    N/A

  • Study Type

    Interventional

  • Status

    Completed No Results Posted

  • Intervention/Treatment

    mirtazapine ...

  • Study Participants

    40
The purpose of this study is to evaluate if the use of antidepressant medication in depressed patients with implantable cardioverter defibrillator reduces the number of ICD's shocks as it improves depressive affect.
episodes of arrhythmia remain present even after icd implantation, this is specially true in depressed patients. it is hypothesized that improving mood state by means of an antidepressant drug . namely mirtazapine. could be responsible of alleviating the number of appropriate shocks delivered by the cardioverter. this could be due to a direct effect of the drug itself or an indirect effect of improving anxious and depressive affect. the mood and anxiety state are measured with the HADS scale
Study Started
Apr 30
2007
Primary Completion
Apr 30
2008
Study Completion
Nov 30
2008
Last Update
Aug 18
2009
Estimate

Drug mirtazapine

mirtazapine 15 mg daily tablets

  • Other names: mirtazapine 1500 mtz

Drug mirtazapine

15 mg daily

  • Other names: remeron 1569 rem

mirtazapine Placebo Comparator

mirtazapine, sugar pill Placebo Comparator

Criteria 

Inclusion Criteria:

cardioverter implanted patients
depression
anxiety

Exclusion Criteria:

heart failure
other diseases reducing physical fitness
No Results Posted