Title
Effect of Korean Red Ginseng (KRG) on Dry Mouth
PMS Clinical Study of Korean Red Ginseng Powder on Dry Mouth and Salivary Flow Rates in Xerostomatic Populations
Phase
Phase 4Lead Sponsor
The Korean Society of GinsengStudy Type
InterventionalStatus
Completed Results PostedIndication/Condition
XerostomiaIntervention/Treatment
ginseng ...Study Participants
100The purpose of this study is to determine the effect of KRG (Korean Red Ginseng) on Dry Mouth (Xerostomia).
Korean Red Ginseng
Worldwide use
A main herb of old oriental prescriptions for dry mouth
Need for correct information by RCT
Generic name: Korean Red Ginseng Powder Capsule Original herb name: Panax ginseng Form and contents: Capsule with powder of steamed root of 6-year Panax ginseng Dosage and frequency: 6 g per day (twice a day), Oral administration Administration duration: 56 days in the study
There is no specific name because this intervention is placebo. This placebo has the same form, color and flavor as Korean Red Ginseng Powder Capsule. The dosage form, dosage, frequency and duration is also same as experimental intervention (Korean Red Ginseng Powder Capsule). Main contents: corn-starch with Panax ginseng flavor
The brand name of experimental drug is 'Capsule of Korean Red Ginseng Powder'. It consists of the powder of steamed root of Panax ginseng made by Korean Ginseng Corp.
The placebo of this study is corn-starch powder with Korean Red Ginseng flavor. It has the same shape, color and flavor like experimental drug.
Inclusion Criteria: Dry mouth patients Exclusion Criteria: Sjögren syndrome Irradiation related xerostomia Severe psychiatric diseases pregnancy or breast feeding women
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Visual Analogue Scale of Subjective Dry Mouth is 10 cm, where 0 cm indicates no dry mouth and 10 cm the severe dry mouth.
Unstimulated salivary flow rates were compared between 0 and 8 weeks in both groups.
Stimulated salivary flow rates were compared between 0 and 8 weeks in both groups.
