Official Title
Hemodynamic Effects of Spironolactone in Patients With Heart Failure
Phase
N/ALead Sponsor
University of ToledoStudy Type
InterventionalStatus
Completed No Results PostedIndication/Condition
Congestive Heart FailureIntervention/Treatment
spironolactone ...Study Participants
18To determine if the beneficial effect of spironolactone in patients with congestive heart failure is in part due to its intrinsic inotropic action.
Randomized, two group placebo controlled, single blind study.
100 mg tablet of Spironolactone (Aldactone) by mouth with half a glass of water.
Inclusion Criteria: CHF 21 - 80 years Serum creatinine < 2 mg/dL Serum potassium 2.7 - 4.5 mg/dL measured within past 4 weeks Exclusion Criteria: Less than 21 years Pregnancy