Trial | NCT00690950  Report issue

Title

A Study to Determine the Improvement of the Symptoms of Benign Prostatic Hyperplasia (BPH) When Switching Subjects From Proscar to Avodart
Switch Study: Are There Any Measurable Differences When Switching Patients on Finasteride Therapy to Dutasteride?

  • Phase

    Phase 4

  • Study Type

    Interventional

  • Status

    Unknown status

  • Study Participants

    50
Hypothesis: Dutasteride will perform better than finasteride in decreasing prostate volume, improving symptoms based on International Prostate Symptom score,and lower pvr based on the scientific information that dutasteride inhibits both Type I and II 5-alpha-reducatase vs. finasteride which only inhibits the Type II enzyme
Study Started
May 31
2008
Primary Completion
Jul 31
2009
Anticipated
Last Update
Jun 05
2008
Estimate

Drug Dutasteride

0.5mg capsule, taken once daily for 12 months

Criteria 

Inclusion Criteria:

Male
Age 50-80
On finasteride for no less than 12 months
Willing to undergo all necessary test in the 12 month evaluation

Exclusion Criteria:

History of medication non-compliance
Unwillingness to undergo/tolerate 2 blood draws
Unwillingness to tolerate/undergo 2 TRUSP
No Results Posted